Materials and methods relating to increasing viral titre

Details Materials and methods relating to increasing viral titre Materials and methods relating to increasing viral titre

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) C12N 7/02 (2006.01)

Patent

CA 2406283

The invention provides methods for increasing viral titre in a sample. The methods utilize specific binding members such as lectins and antibodies to bind the virus particles such that they can be concentrated. The invention further provides methods for isolating viral particles from a sample, e.g. blood. There is also provided materials and methods for targeting viral particles to particular tissues using antibodies or paramagnetic particles.

L'invention concerne des matières et procédés servant à augmenter le titre viral dans un échantillon. Les procédés utilisent des éléments de liaison spéciaux tels que les lectines et d'autres anticorps pour lier les particules de virus afin qu'elles puissent être concentrées. L'invention concerne aussi des procédés pour isoler les particules virales dans un échantillon tel que le sang. Elle se rapporte également à des matières et procédés servant à diriger les particules virales contre des tissus déterminés en utilisant des anticorps ou des particules paramagnétiques.

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