Materials and methods relating to the diagnosis and...

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) A61K 31/70 (2006.01) C07K 16/18 (2006.01) C12Q 1/32 (2006.01) G01N 33/53 (2006.01) G01N 33/66 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2264829

The diagnosis of diabetes based on the level or ratio of P- and A-type inositolphosphoglycans (IPGs) in a sample from a patient, and the use of P- and A-type IPGs or their antagonists in the treatment of diabetes is disclosed. In particular, the present invention provides treatment of IDDM or lean type II diabetes (NIDDM) with a mixture of P- and A-type mediators, and treatment of obese type II diabetes (NIDDM) with a P-type mediator and/or an A- type antagonist.

Diagnostic du diabète basé sur le taux ou le rapport d'inositolphosphoglycannes (IPG) de type P et A dans le prélèvement provenant d'un patient et utilisation des IPG de type P et A ou de leurs antagonistes dans le traitement du diabète. En particulier, la présente invention concerne le traitement du diabète insulinodépendant ou du diabète maigre non insulinodépendant à l'aide d'un mélange de médiateurs de type P et A, ainsi que le traitement du diabète gras non insulinodépendant à l'aide d'un médiateur de type P et/ou d'un antagoniste de type A.

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