Materials and methods relating to the treatment of leukaemias

Details Materials and methods relating to the treatment of leukaemias Materials and methods relating to the treatment of leukaemias

G - Physics

01

N

G01N 33/68 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2404324

The invention provides materials and methods capable of modulating the strong- self-association of chimeric transcription factors to form high molecular weight (HMW) complexes. The invention further provides compounds comprising the oligomerization domains of oligomeric substances and a polypeptide for modulating the activity of that polypeptide intra or inter-cellularly.

L'invention concerne des substances et des méthodes capables de moduler la forte auto-association de facteurs de transcription chimériques pour former des complexes de poids moléculaire élevé. Ladite invention concerne également des composés comportant les domaines d'oligomérisation de substances oligomériques et un polypeptide pour moduler l'activité dudit polypeptide de façon intra- ou inter-cellulaire.

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