C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) A61K 39/12 (2006.01) A61P 17/00 (2006.01) A61P 31/20 (2006.01) A61P 35/00 (2006.01) C07K 14/02 (2006.01) C07K 14/025 (2006.01) C07K 14/35 (2006.01) C12N 7/04 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2691091
Provided is a fusion protein, which comprises human papillomavirus E7 antigen, virus capsid protein and molecular chaperone. Also provided is a macromolecule with immunogenicity aggregated by the fusion proteins. The particle morphology of the macromolecule is different from that of the virus-like particle. The macromolecule can be used for treatment of human papillomavirus relating diseases.
L'invention concerne une protéine de fusion contenant l'antigène du papillomavirus humain E7, une protéine de capside virale et un chaperon moléculaire. L'invention concerne également une macromolécule présentant une immunogénicité agrégée par les protéines de fusion. La morphologie particulaire de la macromolécule est différente de celle de la particule de type virale. Cette macromolécule peut être utilisée dans le traitement des maladies associées au papillomavirus humain.
Cao Yunxu
Kirby Eades Gale Baker
Shanghai Zerun-Ankegens Biopharmaceutical Co. Ltd
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