Maternal immune secretions and their use in the treatment...

A - Human Necessities – 61 – K

Patent

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A61K 35/20 (2006.01) A61K 8/64 (2006.01) A61K 8/98 (2006.01) A61K 35/54 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2297183

Medicaments formed from maternal immune secretion having biological activity characteristic of human saliva and other mucosal secretion and which is tolerated by humans can be used for the treatment and/or prophylaxis of conditions of the human body such as the buccal cavity characterised by a loss of normal mucosal or the normal biological properties thereof. The secretions are suitably egg fluid or milk from a domestic animal or replicas thereof. These secretions can be enriched with the native immunoglobulin found therein so that they have a potency which approximates that of hyperimmunised immunoglobulin. The medicaments have particular application in the treatment and/or prophylaxis of oral infection, dental caries, conditions of the buccal cavity characterised by inflammation, xerostomia and halitosis.

L'invention concerne des médicaments préparés à partir d'une sécrétion immune maternelle possédant une activité biologique, caractéristique de la salive humaine ou d'une autre sécrétion de muqueuse, tolérée par l'homme; on peut utiliser ces médicaments dans le traitement et/ou la prophylaxie d'états du corps humain, comme la perte de l'activité normale des muqueuse de la cavité buccale, ou des propriétés biologiques normales de ces muqueuses. Les sécrétions sont de manière appropriée un fluide d'oeuf ou du lait provenant d'un animal domestique ou de répliques de ceux-ci. On peut enrichir ces sécrétions à l'aide de l'immunoglobuline naturelle trouvée dans ces sécrétions, de façon à leur donner une puissance qui s'approche de celle de l'immunoglobuline hyperimmunisée. Ces médicaments sont notamment utiles dans le traitement et/ou la prophylaxie d'infections buccales, de caries dentaires et d'états de la cavité buccale caractérisés par une inflammation, la xérostomie et l'haleine fétide.

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