Matrix-based pulse release pharmaceutical formulation

Details Matrix-based pulse release pharmaceutical formulation Matrix-based pulse release pharmaceutical formulation

A - Human Necessities

61

K

A61K 9/16 (2006.01)

Patent

CA 2605185

The present invention relates to an oral pulse release pharmaceutical composition, which comprises a polymer matrix core, wherein at least one pharmaceutically active ingredient is distributed within the core and on the outer surface of the core. Amphetamine salts, among a number of other pharmaceutically active ingredients, can be formulated as a pharmaceutical composition described herein. The present invention also provides a method for preparing an immediate release component on a solid pharmaceutical formulation.

L'invention concerne une composition pharmaceutique orale à libération par impulsions qui comprend un noyau matriciel polymère. Au moins un ingrédient actif sur le plan pharmaceutique est distribué dans le noyau et sur la surface extérieure du noyau. Les sels d'amphétamine, parmi un certain nombre d'autres ingrédients actifs sur le plan pharmaceutique, peuvent être formulés sous la forme de la composition pharmaceutique selon l'invention. L'invention concerne également une méthode de préparation d'un composant à libération immédiate sur une formulation pharmaceutique solide.

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