A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/28 (2006.01) A61K 31/485 (2006.01)
Patent
CA 2478523
The invention concerns a storage stable pharmaceutical formulation comprising preferably two active compounds in a non-swellable diffusion matrix, whereby the compounds are released from the matrix in a sustained, invariant and, if several compounds are present, independent manner and the matrix is determined with respect to its substantial release characteristics by ethylcellulose and at least one fatty alcohol. The invention also concerns methods for producing such pharmaceutical formulations.
L'invention concerne une formulation pharmaceutique stable au stockage, qui comprend de préférence deux composés actifs, dans une matrice de diffusion non dilatable. Les composés sont libérés depuis la matrice de façon prolongée et constante, et si plusieurs composés sont présents, de façon indépendante. De plus, la matrice est déterminée en fonction de ses caractéristiques de libération substantielle par l'éthylcellulose et au moins un alcool gras. L'invention concerne également des procédés relatifs à l'élaboration de ce type de formulation pharmaceutique.
Broegmann Bianca
Muehlau Silke
Spitzley Christof
Euro-Celtique S.a.
Gowling Lafleur Henderson Llp
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