Matrix for sustained-release preparation

Details Matrix for sustained-release preparation Matrix for sustained-release preparation

C - Chemistry, Metallurgy

08

G

C08G 63/91 (2006.01) A61K 9/16 (2006.01) A61K 38/09 (2006.01) A61K 38/19 (2006.01) A61K 47/34 (2006.01) C08G 63/06 (2006.01)

Patent

CA 2143044

The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.

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