C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 38/39 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/78 (2006.01) C07K 19/00 (2006.01) C12N 5/02 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2440743
The present invention is directed to polypeptides which can be used to stimulate cell growth and/or division. More particularly, the present invention is directed to polypeptides which can be used to stimulate mesenchymal cell growth and/or division. The invention also relates to a method for transfecting chondrocytes and other mesenchymal cells with vectors carrying genes capable of stimulating chondrogenesis, osteogenesis, growth, repair, regeneration and/or restoration of the cellular matrix.
La présente invention concerne des polypeptides qui peuvent être utilisés pour stimuler la croissance et/ou la division cellulaire(s). De manière plus particulière, l'invention concerne des polypeptides qu'on peut utiliser pour stimuler la croissance et/ou la division des cellules mésenchymateuses; un procédé permettant de transfecter des chondrocytes et d'autres cellules mésenchymateuses avec des vecteurs portant des gènes qui sont capables de stimuler la chondrogenèse, l'ostéogenèse, la croissance, la réparation et/ou la restauration de la matrice cellulaire.
Ghosh Peter
Roubin Rebecca
Chondrogenesis Pty Ltd
Gowling Lafleur Henderson Llp
The University Of Sydney
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