Maturation of dendritic cells with immune response modifying...

Details Maturation of dendritic cells with immune response modifying... Maturation of dendritic cells with immune response modifying...

C - Chemistry, Metallurgy

12

N

C12N 5/0784 (2010.01) A61K 35/14 (2006.01) A61K 39/00 (2006.01) A61K 39/39 (2006.01) A61P 35/00 (2006.01) A61K 31/437 (2006.01)

Patent

CA 2362377

A method of inducing the maturation of dendritic cells by stimulating immature dendritic cells with an imidazoquinoline type immune response modifying compound. Dendritic cells that have been matured in this manner display increased antigen presenting ability and may be used as immunotherapeutic agents.

L'invention concerne un procédé permettant d'induire la maturation de cellules dendritiques par la stimulation de cellules dendritiques immatures à l'aide d'un composé de type imidazoquinoline modifiant la réponse immunitaire. Les cellules dendritiques ayant été traitées de cette manière présentent une plus grande abilité présentatrice d'antigènes et peuvent être utilisées comme agents immunothérapeutiques.

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