Maxs as modifiers of the axin pathway and methods of use

Details Maxs as modifiers of the axin pathway and methods of use Maxs as modifiers of the axin pathway and methods of use

G - Physics

01

N

G01N 33/00 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2494240

Human MAX genes are identified as modulators of the AXIN pathway, and thus are therapeutic targets for disorders associated with defective AXIN function. Methods for identifying modulators of AXIN, comprising screening for agents that modulate the activity of MAX are provided.

L'invention concerne des gènes MAX humains identifiés comme modulateurs de la voie de l'Axine et constituant ainsi des cibles thérapeutiques pour les troubles associés à une fonction Axine défectueuse. L'invention concerne également des méthodes d'identification de modulateurs de l'Axine consistant à rechercher par criblage des agents modulant l'activité de MAX.

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