Maytansinoid-antibody conjugate compositions

Details Maytansinoid-antibody conjugate compositions Maytansinoid-antibody conjugate compositions

A - Human Necessities

61

K

A61K 47/48 (2006.01)

Patent

CA 2525553

The invention provides a liquid composition and a Iyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.

L'invention concerne une composition liquide et une composition lyophilisée comprenant une quantité thérapeutiquement efficace d'un conjugué comprenant un anticorps chimiquement couplé à un maytansinoïde. L'invention concerne également une méthode pour tuer une cellule chez un humain consistant à administrer à l'humain l'une desdites compositions de sorte que l'anticorps se fixe à la surface de la cellule et que la cytotoxicité du maytansinoïde est activée, la cellule étant ainsi tuée.

Affiliated with

Also associated with

Rating

Maytansinoid-antibody conjugate compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Maytansinoid-antibody conjugate compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Maytansinoid-antibody conjugate compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1573502