C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/237.1
C07D 498/18 (2006.01)
Patent
CA 1135261
Abstract of the Disclosure Novel maytansinoids of the formula: Image wherein X is H or C?, and Y is C?, OH, SH, CN, NO2, -OR or -S(O)nR wherein R is alkyl, aryl, aralkyl or azaheterocyclic group which may be substituted, and n is O, 1 or 2, have antimitotic, antitumor and antimicrobial activities.
353737
Akimoto Hiroshi
Miyashita Osamu
Fetherstonhaugh & Co.
Takeda Chemical Industries Ltd.
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