C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/72 (2006.01) C07K 14/68 (2006.01) C07K 14/685 (2006.01) G01N 33/566 (2006.01) G01N 33/74 (2006.01) G01N 33/94 (2006.01)
Patent
CA 2340323
The present invention relates to drug screening assays and therapeutic methods for the treatment of addictive behavior disorders, such as cocaine and morphine addiction utilizing the melanocortin 4-receptor (MC4-R) as the target for intervention. The invention also relates to compounds that antagonize the activity or expression of the MC4-R, and the use of such compounds in the treatment of addictive behavior disorders.
L'invention concerne des essais de criblage de médicaments et des procédés thérapeutiques permettant de traiter les troubles liés à la dépendance par rapport à des produits comme la cocaïne et la morphine, consistant à utiliser le récepteur de la mélanocortine 4 comme cible pour l'intervention. L'invention concerne également des composés qui sont antagonistes vis-à-vis de l'activité ou de l'expression de ce récepteur, ainsi que l'utilisation desdits composés dans le traitement des troubles considérés.
Smart & Biggar
Yale University
LandOfFree
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