C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/90 (2006.01) A61K 38/00 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2608315
The present invention relates to the use of the human or animal MCM9 gene, or parts of said gene, or transcripts thereof, or antisense nucleic acids able to hybridize with part of said gene or transcripts, or silencing RNA derived from parts of said transcripts and able to repress said MCM9 gene, or proteins or peptidic fragments translated from said transcripts, or antibodies directed against said proteins or peptidic fragments, for the preparation of a pharmaceutical composition for the treatment of a human or animal pathology linked to a dysfunction of the expression of the MCM9 gene, or of human or animal cancers.
Utilisation de gène MCM9 humain ou animal, ou de parties, ou de transcriptions, ou d'acides nucléiques antisens, capables de s'hybrider avec une partie de ce gène ou de transcriptions, ou de rendre silencieux l'ARN dérivé de parties de ces transcriptions et de réprimer le gène en question, ou fragments protéiniques ou peptidiques convertis depuis ces transcriptions, ou bien anticorps orientés contre les fragments considérés, pour la préparation de composition pharmaceutique permettant de traiter une pathologie humaine ou animale liée à un dysfonctionnement de l'expression du gène décrit ou les cancers chez l'homme ou l'animal.
Lutzmann Malik
Maiorano Domenico
Mechali Marcel
Centre National de La Recherche Scientifique
Goudreau Gage Dubuc
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