Mdr1 snp in acute rejection

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2611188

The present invention concerns a method for the prediction of acute renal transplant rejection by detecting a polymorphism in exon 26 of the MDRl gene, optionally in combination with polymorphisms of the IMPDH2 and IL 10 genes which were found to be associated with this disease.

L'invention concerne un procédé de prédiction de rejet de transplantation rénale aigu par détection d'un polymorphisme dans un exon 26 du gène MDR1, éventuellement en combinaison avec des polymorphismes des gènes IMPDH2 et IL 10 dont on a découvert qu'ils étaient associés à cette maladie.

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