Means and methods for monitoring non-nucleoside reverse...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/70 (2006.01) C12N 15/48 (2006.01) C12N 15/54 (2006.01) C12N 15/64 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2329140

This invention relates to antiviral drug susceptibility and resistance tests to be used in identifying effective drug regimens for the treatment of human immunodificiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) and further relates to the means and methods of monitoring the clinical progression of HIV infection and its response to antiretroviral therapy, particularly non-nucleoside reverse transcriptase inhibitor therapy using phenotypic susceptibility assays or genotypic assays.

La présente invention concerne des tests de susceptibilité et de résistance aux médicaments antiviraux pour la recherche de posologies médicamenteuses convenant au traitement de l'infection par le VIH et au traitement du SIDA. L'invention concerne également des moyens et des procédés permettant de faire un suivi clinique de l'évolution de l'infection par le VIH et sa réponse à la thérapie antirétrovirale, et plus particulièrement la thérapie antirétrovirale des inhibiteurs de transcriptase inverse des non-nucléosides par utilisation d'essais de susceptibilité phénotypiques ou d'essais génotypiques.

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