Means and methods for the differentiation of cardiac and...

G - Physics – 01 – N

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G01N 33/74 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2593304

The present invention relates to a method for differentiating in a subject suffering from acute shortness of breath (dyspnea) between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes comprising the steps of determining the amount of SP-B in a sample of a subject, determining the amount of a natriuretic peptide in a sample of said subject, and differentiating between (i) a pulmonary disease, (ii) a cardiovascular complication, (iii) a cardiovascular complication accompanied by a pulmonary disease or (iv) acute dyspnea without cardiovascular or pulmonary causes by comparing the determined amounts with reference amounts. Moreover, the present invention relates to a device and a kit for carrying out said method.

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