A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/14 (2006.01)
Patent
CA 2634349
The present invention relates of the use of certain inner ionic (zwitter ionic) phospholipids, phosphonolipids and phosphate derivatives for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of an immunological disorder related to mast cell sensitization and/or activation. Preferred in this context are Edelfosine, Miltefosine and Perifosine. In a particularly preferred embodiment, the present invention relates to the use of Miltefosine for the preparation of a pharmaceutical composition for the treatment, prevention and/or amelioration of allergic diseases, in particular acute hyperallergic diseases, like asthma, atopic dermatitis and mastocytosis.
La présente invention concerne l'emploi de certains dérivés zwitterioniques de phospholipides, de phosphonolipides et de phosphates dans l'élaboration d'une préparation pharmaceutique pour le traitement, la prévention et/ou le soulagement d'un trouble immunologique lié à la sensibilisation et/ou l'activation des mastocytes. Dans ce contexte, on utilise de préférence l~Édelfosine, la Miltéfosine et la Périfosine. Dans un mode d'application particulièrement préféré, la présente invention concerne l'emploi de la Miltéfosine dans l'élaboration d'une préparation pharmaceutique pour le traitement, la prévention et/ou le soulagement de maladies allergiques, en particulier de maladies hyperallergiques aiguës, comme l'asthme, la dermatite atopique et la mastocytose.
Braxmeier Tobias
Friedrichson Tim
Jennings Gary
Goudreau Gage Dubuc
Jado Technologies Gmbh
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