Means for improving cognitive functions and memory based on...

A - Human Necessities – 61 – K

Patent

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A61K 31/444 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2671321

A means for improving cognitive functions and memory based on hydrogenated pyrido (4, 3-b) indoles (variants), a pharmacological means based thereon and a method for the use thereof relate to the use of chemical compounds in the field of medicine and may be used to extend the arsenal of means which can be utilized for substantial enhancement of memory and activation of the learning process, for the treatment of impaired cognitive functions and memory in the elderly and in mild cognitive impairment, in brain trauma, in chronic cerebrovascular insufficiency, in hypoxic encephalopathies, resulting from chronic alcoholism and in delayed development in children. Said task is resolved by the use of hydrogenated pyrido ( [4, 3-b] ) indoles of formula (1) or formula (2) as means for improving cognitive functions and memory.

Le moyen à base de pyrido[4,3-b]indoles hydrogénés (variants) permettant d'améliorer les fonctions cognitives et la mémoire, le moyen pharmacologique fondé sur ce premier moyen et le procédé d'utilisation de ce moyen qui font l'objet de la présente invention sont liés à l'emploi de composés chimiques dans le domaine médical et peuvent être utilisés pour augmenter l'arsenal des outils susceptibles de se révéler utiles à l'amélioration substantielle de la mémoire et à l'activation du procédé d'apprentissage, pour le traitement d'une détérioration des fonctions cognitives et de la mémoire chez les personne âgées ainsi que d'une déficience cognitive légère, d'un traumatisme cérébral, d'une insuffisance cérébrovasculaire chronique, d'encéphalopathies hypoxiques résultant d'un alcoolisme chronique et d'un retard de développement chez les enfants. Ladite tâche est résolue par l'utilisation de pyrido[4,3-b]indoles répondant à la formule (1) ou à la formule (2) en tant que moyen permettant l'amélioration des fonctions cognitives et de la mémoire.

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