Means for the identification of compounds capable of...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2423111

The present application relates to transgenic animals over-expressing KARAP, knock-in animals bearing non functional KARAP, and to method and kits for the identification of compounds capable of inhibiting a KARAP-transduced immune signal.

L'invention concerne des animaux transgéniques de KARAP surexprimé, des animaux transgéniques porteurs de KARAP non fonctionnel, un procédé et des assemblages d'identification de composants capables d'inhiber un signal immunitaire transduit-KARAP.

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