Measurement and uses of oxidative status

G - Physics – 01 – N

Patent

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G01N 33/483 (2006.01)

Patent

CA 2684144

The present invention provides a method of determining the overall oxidative status of a body fluid or a tissue of a patient by measuring the oxidation-reduction potential (ORP) of the body fluid or tissue. The method has been found to be useful in the diagnosis, evaluation and monitoring of patients who have suffered a trauma (such as a head injury), patients suspected of being critically-ill, patients who have a viral infection, and patients suspected of having a myocardial infarction. The method has also been found useful in monitoring and evaluating exercise performance in patients. In addition, the method has been found useful in monitoring and evaluating stored blood products and patients who will receive such a product.

La présente invention concerne un procédé de détermination du statut d'oxydation globale d'un fluide corporel ou d'un tissu d'un patient en mesurant le potentiel d'oxydoréduction (ORP) du fluide corporel ou du tissu. Le procédé s'est avéré utile pour le diagnostic, l'évaluation et la surveillance de patients qui ont souffert d'un traumatisme (tel qu'une lésion à la tête), des patients suspectés d'être dans un état critique, des patients qui ont une infection virale et des patients suspectés d'avoir un infarctus du myocarde. Le procédé s'est également avéré être utile pour la surveillance et l'évaluation de la performance d'exercice chez des patients. De plus, le procédé s'est avéré utile pour la surveillance et l'évaluation de produits sanguins stockés et de patients qui recevront un tel produit.

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