Measurement methods and systems

A - Human Necessities – 61 – D

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Details

A61D 7/04 (2006.01) A61B 5/08 (2006.01) A61B 5/083 (2006.01) A61M 15/00 (2006.01) A61M 16/00 (2006.01)

Patent

CA 2192571

In a method for measuring a dose of a drug inhaled by an animal, the momentary concentration of the drug in an aerosol supplied to the animal is determined as well as the momentary inhalation flow rate of the animal. An inhaled partial dose is calculated from each determined inhalation flow rate value and a corresponding concentration value. The calculated inhaled partial doses are added up to obtain the total dose inhaled by the animal. When a predetermined dose is to be administered to the animal, the inhaled partial doses are successively cumulated and compared with the predetermined dose. The aerosol generation is interrupted as soon as the predetermined dose is achieved. Systems for carrying the methods into effect are disclosed.

Selon un procédé de mesure d'une dose d'un médicament inhalé par un animal, on détermine la concentration instantanée du médicament dans un aérosol administré à l'animal ainsi que le débit d'inhalation instantané de celui-ci. On calcule une dose partielle inhalée à partir de chaque valeur de débit d'inhalation déterminée ainsi que d'une valeur de concentration correspondante. Les doses partielles ainsi calculées sont additionnées afin de donner la dose totale inhalée par l'animal. Lorsque l'on doit administrer une dose prédéterminée à l'animal, les doses partielles inhalées sont successivement cumulées et comparées à la dose prédéterminée. La génération de l'aérosol est interrompue dès que la dose prédéterminée est atteinte. Des systèmes permettant de mettre en oeuvre ces procédés sont également décrits.

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