Measurement of arylesterase enzymatic activity and...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C12Q 1/44 (2006.01)

Patent

CA 2702121

The present invention concerns a method for detecting the presence of or predisposition to autism, an autism spectrum disorder, or an autism-associated disorder in a subject, the method comprising measuring an arylesterase enzymatic activity in a sample from the subject, optionally combined with the determination of alleles of PON1 polymorphisms.

La présente invention concerne un procédé permettant de détecter la présence d'un autisme ou une prédisposition à l'autisme, un trouble du spectre de l'autisme, ou un trouble associé à l'autisme chez un sujet. Ledit procédé comprend la mesure d'une activité enzymatique arylestérase dans un échantillon prélevé sur le sujet, éventuellement combinée à la détermination d'allèles de polymorphismes PON1.

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