C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/52 (2006.01) C12Q 1/48 (2006.01)
Patent
CA 2681822
The present invention relates to a method for measuring the activity of a kynurenine-converting enzyme, of a kynurenic acid, anthranilic acid and/or 3-hydoxykynurenine-producing enzyme, comprising the step of measuring the activity in the presence of an interfering sample, preferably chosen from a CSF (cerebrospinal liquid) or serum, and the detection of the conversion from kynurenine, kynurenic acid, anthranilic acid and/or 3-hydroxykynurenine.
L'invention concerne un procédé de mesure de l'activité d'une enzyme transformant de la kynurénine et/ou d'une enzyme produisant de l'acide kynurénique, de l'acide anthranilique et/ou de la 3-hydroxykynurénine. Ledit procédé consiste à mesurer l'activité en présence d'un échantillon interférant de préférence choisi entre du liquide cérébrospinal ou du sérum, et à détecter la transformation de l'acide kynurénique, de l'acide anthranilique et/ou de la 3-hydroxykynurénine.
Baran Halina
Kepplinger Berthold
Ridout & Maybee Llp
LandOfFree
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