Measuring caspase 3 activity to determine viral stability

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/02 (2006.01) A01N 63/00 (2006.01) A61K 49/00 (2006.01) C12Q 1/37 (2006.01) C12Q 1/70 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2373250

Viral induction of caspase 3 activity was found to provide a reliable measure of viral activity. Assaying viral induction of caspase 3 activity can be used, for example, in methods for measuring viral potency and stability, and for evaluating the stability of a virus in different formulations.

On a découvert que l'induction virale de l'activité de la caspase 3 fournit une mesure fiable de l'activité virale. Un dosage de l'induction virale de l'activité de la caspase 3 peut être utilisé, par exemple, dans des méthodes de mesure de la puissance et de la stabilité virales, et pour évaluer la stabilité d'un virus dans différentes formulations.

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