Measuring molecular change in the ocular lens

Details Measuring molecular change in the ocular lens Measuring molecular change in the ocular lens

A - Human Necessities

61

B

A61B 3/10 (2006.01) A61B 3/117 (2006.01) A61B 5/00 (2006.01)

Patent

CA 2113268

Apparatus and methods for noninvasively diagnosing diabetes mellitus, the prediabetic condition, cataracts, and other diseases in the human (or other) body are disclosed. Diagnoses are made by illuminating ocular lens (L) or other tissue with a narrowband light source (15) at a selected wavelength, separating the backscattered radiation into fluorescent and Rayleigh components (55, 135), detecting (85) the backscattered radiation intensity at the peak of the fluorescent response, and normalizing the detected value with the detected intensity of its Rayleigh component. Measurements provided in this manner can be used as improved indicators of the presence or absence of certain diseases or conditions.

Divulgation d'un appareil et de méthodes pour diagnostiquer sans effraction le diabète sucré, la condition prédiabétique, les cataractes et d'autres maladies affectant le corps humain (ou autre). Des diagnostics sont posés en illuminant le cristallin (L) ou un autre tissu avec une source lumineuse de bande étroite (15) à une longueur d'onde sélectionnée, en séparant les rayonnements rétrodiffusés en composantes fluorescente et de Rayleigh (55, 135), en détectant (85) l'intensité des rayonnements rétrodiffusés au pic de la réponse fluorescente et en normalisant la valeur détectée avec l'intensité détectée de sa composante de Rayleigh. Les mesures ainsi obtenues peuvent servir d'indicateurs améliorés de la présence ou de l'absence de certaines maladies ou conditions.

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