Mecano growth factor peptides and their use

Details Mecano growth factor peptides and their use Mecano growth factor peptides and their use

C - Chemistry, Metallurgy

07

K

C07K 14/65 (2006.01) A61K 38/08 (2006.01) A61K 38/30 (2006.01) A61P 9/00 (2006.01) A61P 21/00 (2006.01) A61P 25/00 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2601227

This invention relates to biologically active polypeptides derived from the E peptide that forms the C-terminus of the insulin-like growth factor I (IGF-I) splice variant known as mechano growth factor (MGF). These peptides are modified to improve their stability compared to the naturally occurring E peptide.

L~invention concerne des polypeptides biologiquement actifs dérivés du peptide E qui forme la partie terminale C de la variante de l~épisse du facteur de croissance I (IGF-I) analogue à l'insuline connu sous le nom de facteur de croissance mécano (MGF). Ces peptides sont modifiés pour améliorer leur stabilité par rapport au peptide E naturel.

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