A - Human Necessities – 61 – M
Patent
A - Human Necessities
61
M
A61M 25/10 (2006.01) A61K 9/127 (2006.01) A61M 29/00 (2006.01) A61N 1/30 (2006.01) A61P 9/00 (2006.01)
Patent
CA 2526508
A mechanical dilatation and medicament delivery device (11) for enlarging a flow passage by dilating and delivering a liposome or micelle-encapsulated therapeutic agent to an obstruction in the vessel. The invention comprises a substantially cylindrically shaped expansion member (31) and includes a means engaged to the expansion member for altering the distance between the proximal end and the distal end of the expansion member by transforming the expansion member between a diametrically contracted configuration to diametrically expanded configuration. A liposome or micelle-encapsulated therapeutic agent or medicament is coated on either the expansion member, or incorporated into a substrate coated on the expansion member.
L'invention concerne un dispositif de dilatation mécanique et de délivrance de médicament (11), permettant d'élargir un passage de flux par dilatation, et d'assurer la délivrance d'agent thérapeutique à encapsulation par liposome ou micelle à destination d'un vaisseau obstrué. On décrit un élément d'expansion sensiblement cylindrique (31), avec système enclenché à lui, pour la modification de la distance entre l'extrémité proximale et l'extrémité distale de l'élément d'expansion, par transformation de l'élément entre une configuration à contraction diamétrale et une configuration à expansion diamétrale. Un agent thérapeutique ou médicament à encapsulation par liposome ou micelle est appliqué en revêtement sur l'élément d'expansion, ou incorporé à un substrat appliqué en revêtement sur ledit élément.
Scott Neal
Segal Jerome
Scott Neal
Segal Jerome
Smart & Biggar
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