Mechanical stress induced genes, expression products...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2332150

This disclosure relates to osteoporosis. Moreover, the disclosure relates to mechanical stress induced genes, probes therefor, tests to identify such genes, expression products of such genes, uses for such genes and expression products, e.g., in diagnosis (for instance risk determination), treatment, prevention, or control, of osteoporosis or factors or processes which lead to osteoporosis; and, to diagnostic, treatment, prevention, or control methods or processes, as well as compositions therefor and methods or processes for making and using such compositions.

L'invention concerne l'ostéoporose. L'invention concerne également des gènes induits par la contrainte mécanique, des sondes destinées à ces gènes, des tests d'identification de ces gènes, des produits d'expression de ces gènes, les utilisations de ces gènes et de ces produits d'expression, notamment dans le diagnostic (par exemple, l'évaluation de risques), le traitement, la prévention de l'ostéoporose ou des facteurs ou processus qui entraînent l'ostéoporose. L'invention concerne également les utilisations de ces gènes et de ces produits d'expression dans la lutte contre l'ostéoporose ou lesdits facteurs ou processus. L'invention concerne également des méthodes de diagnostic, de traitement, de prévention et de lutte, ainsi que des compositions associées et des méthodes de fabrication et d'utilisation de ces compositions.

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