Mechanically competent natural polymer based porous grafts...

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/20 (2006.01) A61F 2/28 (2006.01) A61L 27/24 (2006.01) A61L 27/54 (2006.01) C08B 15/00 (2006.01)

Patent

CA 2752889

The invention provides a scaffold for bone or cartilage replacement, in which the scaffold is fabricated from naturally derived polymers. In one embodiment the invention provides a bone replacement scaffold, wherein the scaffold comprises sintered polysaccharide microspheres. In a particular embodiment the invention provides a bone replacement scaffold, in which the scaffold comprises polysaccharide microspheres comprising ethyl cellulose microspheres and/ or cellulose acetate microspheres. The invention further includes methods of making bone replacement scaffolds and methods of treating bone injury in an animal.

L'invention porte sur un échafaudage pour un remplacement d'os ou de cartilage, l'échafaudage étant fabriqué à partir de polymères d'origine naturelle. Dans un mode de réalisation, l'invention porte sur un échafaudage de remplacement osseux, l'échafaudage comprenant des microsphères de polysaccharide fritté. Dans un mode de réalisation particulier, l'invention porte sur un échafaudage de remplacement osseux, l'échafaudage comprenant des microsphères de polysaccharide comprenant des microsphères d'éthyl cellulose et/ou des microsphères d'acétate de cellulose. L'invention comprend en outre des procédés de fabrication d'échafaudage de remplacement osseux et des procédés de traitement de lésion osseuse chez un animal.

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