A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/26 (2006.01) A61K 9/20 (2006.01) A61K 9/50 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2072933
The application discloses a process for the manufac- ture of mechanically-stable, readily-disintegratable tablets made of small preformed, preferably rounded, particles or pellets containing a high percentage of active ingredient in which - prior to compression - the particles are coated with an aqueous or aqueous/organic suspension containing water-soluble polyvinyl alcohol having an ester content of 19.4 to 6.7%, a disintegrant, and finely-divided cellulose, the remainder being excipients such as addition- al colloids, adjuvants, dyes, and/or flavors and the suspending liquid, and dried, the stable but readily- friable tablet product thus-produced, and a method of delivering an active ingredient by the employment of such a tablet for oral ingestion.
Kuehn Bernd
Nuernberg Eberhard
Seiller Erhard
Merz + Co. Gmbh & Co.
Merz Pharma Gmbh & Co. Kgaa
Perley-Robertson Hill & Mcdougall Llp
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