Mechanism of action of primary cell derived biologic

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2762314

A method of treating an immune target that is suppressing the immune system and restoring the immune system, including the steps of administering an effective amount of a primary cell derived biologic, modifying populations of B and T cells in blood, activating regional lymph nodes, infiltrating an area adjacent to an immune target with T helper and B cells, infiltrating the immune traget with T killer cells and macrophages, and treating the immune target and restoring the immune system. A method of inducing immunization in a patient. A method of destroying a tumor. A method of predicting a favorable treatment outcome to cancer treatment. A method of immune prophylaxis. A method of immune restoration. A method of treating a tumor. A method of preventing tumor escape.

L'invention concerne un procédé de traitement d'une cible immune, c'est-à-dire la suppression du système immunitaire et la restauration du système immunitaire, comprenant l'administration d'une quantité efficace d'agent biologique dérivé d'une cellule primaire, la modification de populations de lymphocytes B et T dans le sang, l'activation de ganglions lymphatiques régionaux, l'infiltration d'une zone adjacente à une cible immune avec des lymphocytes T auxiliaires et B, l'infiltration de la cible immune avec des lymphocytes T tueurs et des macrophages, le traitement de la cible immune et la restauration du système immunitaire. L'invention concerne également un procédé consistant à induire une immunisation chez un patient, un procédé de destruction d'une tumeur, un procédé de prévision d'un résultat thérapeutique favorable pour le traitement du cancer, un procédé de prophylaxie immune, un procédé de restauration immunitaire, un procédé de traitement d'une tumeur et un procédé empêchant la fuite d'une tumeur.

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