Mediator-modified redox biomolecules for use in...

Details Mediator-modified redox biomolecules for use in... Mediator-modified redox biomolecules for use in...

C - Chemistry, Metallurgy

07

F

C07F 15/00 (2006.01) C07F 17/00 (2006.01) G01N 27/26 (2006.01)

Patent

CA 2575436

Compositions and methods for electrochemical detection of an analyte comprising a transition metal compound (I) wherein M is a metallic element that can form a coordinate bond to nitrogen; R and R~ are coordinated to M at their nitrogen atoms; L is a linking ligand; Z is chlorine or bromine; m can be from 1 to 6 and X is an anion, or combination of anions, that balances the charge m. Also provided are electrochemical tags and methods of detection.

L'invention concerne des compositions et des procédés de détection électrochimique d'un analyte comprenant un composé de métal de transition (I), où M représente un élément métallique pouvant former une liaison de coordination à l'azote; R et R' sont coordonnés à M au niveau de leurs atomes d'azote; L désigne un ligand de liaison; Z représente du chlore ou du brome; m peut prend une valeur comprise entre 1 et 6 et X désigne un anion ou une combinaison d'anions équilibrant la charge m. L'invention concerne également des étiquettes électrochimiques et des procédés de détection.

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