Mediator-stabilized reagent compositions for use in...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/00 (2006.01) C12Q 1/32 (2006.01) G01N 27/30 (2006.01) G01N 27/403 (2006.01)

Patent

CA 2699978

The claimed subject matter relates to the stabilization of 1,2-quinone mediators, especially those containing 1,10-phenanthroline quinone (PQ) and more especially transition metal complexes of PQ, in the presence of enzymes when contained in dry reagent layers for biosensor electrodes, through the use of various metal salts, particularly those of lithium.

L'invention concerne la stabilisation de médiateurs 1,2-quinone, spécialement ceux contenant de la 1,10-phénanthroline quinone (PQ) et plus spécifiquement, des complexes de métaux de transition de PQ, en présence d'enzymes lorsqu'elles sont contenues dans des couches de réactif sèches pour des électrodes de biocapteur, par l'utilisation de divers sels de métaux, en particulier ceux de lithium.

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