Mediators useful in an electrochemical biosensor

Details Mediators useful in an electrochemical biosensor Mediators useful in an electrochemical biosensor

G - Physics

01

N

G01N 27/327 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2224034

Disclosed herein is the use of a variety of diazacyanines as mediators for the electrochemical oxidation of NADH/NADPH to NAD+/NADP+, which are reduced by an oxireductase, also present in the system. By applying the mediator together with NADH/NADPH to the surface of a working electrode, the voltage necessary to achieve the desired oxidation is substantially reduced.

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