Medical adhesive and methods of tissue adhesion

A - Human Necessities – 61 – L

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A61L 24/04 (2006.01) A61L 24/00 (2006.01)

Patent

CA 2638022

A method of adhering biological tissue that includes applying a bio-degradable adhesive to the tissue. The adhesive includes a moisture-curable, isocyanate- functional component prepared by reacting (a) a multi-functional isocyanate component and (b) a multi-functional active hydrogen component that includes at least 30% by weight, based upon the total weight of the multi-functional active hydrogen component, of a multi-functional active hydrogen reactant having an equivalent weight less than 100. The ratio R of active hydrogen groups to isocyanate groups can be less than 1Ø

L'invention concerne une méthode d'adhésion de tissu biologique qui consiste à appliquer un adhésif biodégradable à un tissu. L'adhésif comporte un composant réagissant à l'humidité à fonction isocyanate préparé en faisant réagir (a) un composant isocyanate multi-fonctionnel et (b) un composant hydrogène actif multi-fonctionnel qui inclut au moins 30% en poids, basé sur le poids total du composant hydrogène actif multi-fonctionnel, d'un réactif d'hydrogène actif multi-fonctionnel ayant un poids équivalent inférieur à 100. La proportion R des groupes hydrogène actif par rapport aux groupes isocyanate peut être inférieure à 1,0.

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