Medical articles having enhanced therapeutic agent binding

Details Medical articles having enhanced therapeutic agent binding Medical articles having enhanced therapeutic agent binding

A - Human Necessities

61

L

A61L 31/16 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 31/10 (2006.01)

Patent

CA 2638218

According to an aspect of the present invention, medical articles are provided which comprise the following (a) a polymeric region having a first charge, and (b) a charged therapeutic agent having a second, charge that is opposite in sign to that of the first charge. In certain beneficial embodiments, the medical articles are high surface area articles, for example, articles formed using small diameter (e.g., 10 microns or less) fibers.

La présente invention concerne des articles médicaux qui comprennent ce qui suit : (a) une région polymérique à première charge, (b) un agent thérapeutique chargé à seconde charge qui est opposée à celle de la première charge. Dans certains modes de réalisation avantageux, les articles médicaux sont des articles à superficie élevée, par exemple des articles formés en utilisant des fibres d'un diamètre faible (p. ex. de 10 microns ou moins).

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