Medical composition for promotion of skin regeneration

A - Human Necessities – 61 – K

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A61K 47/36 (2006.01) A61K 9/06 (2006.01) A61K 31/198 (2006.01) A61K 31/7004 (2006.01) A61P 17/02 (2006.01) A61L 27/60 (2006.01)

Patent

CA 2607912

Disclosed is a medical composition which, in autotransplantation which is the only method that can induce the epithelialization even in a widespread full- thickness skin defect, enables the fixation of an autotransplantation skin graft in a simple manner and can increase the efficiency of epithelialization to promote the regeneration of the skin. A medical composition comprising a photocrosslinkable chitosan derivative and an amino acid and/or a saccharide. The amino acid is preferably an essential amino acid, and the saccharide is preferably a neutral saccharide selected from glucose, galactose, mannose and fucose.

La présente invention concerne une composition médicale qui, dans une autogreffe qui est le seul procédé qui puisse induire l~épithélialisation même dans le cas d'un défaut de la peau largement diffusé dans toute l~épaisseur, permette la fixation d~une greffe de peau par autogreffe d~une façon simple et qui puisse augmenter l~efficacité de l~épithélialisation pour promouvoir la régénération de la peau. L'invention concerne également une composition médicale comprenant un dérivé de chitosane réticulable à la lumière et un acide aminé et/ou un saccharide. L~acide aminé est de préférence un acide aminé essentiel, et le saccharide est de préférence un saccharide neutre choisi parmi le glucose, le galactose, le mannose et le fucose.

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