Medical device articles formed from polymer-inorganic...

A - Human Necessities – 61 – L

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A61L 27/44 (2006.01) A61L 29/12 (2006.01) A61L 31/12 (2006.01) A61M 25/00 (2006.01) C08L 31/02 (2006.01) C08L 31/04 (2006.01) C08L 67/02 (2006.01)

Patent

CA 2623808

A shaped medical device article prepared from a polymer melt composition comprising a polymer ester, a transesterification catalyst, and a tri- or tetraalkoxy silane, by forming and solidifying said composition, and after solidification, subjecting the composition to reaction conditions to effect hydrolysis of at least some alkoxysilyl groups remaining in the composition to form silanol groups and to effect condensation of said silanol groups to form a ceramic network. The polymer ester may be a vinyl ester homopolymer or copolymer, or a polymer having ester groups in the backbone thereof.

L'invention concerne un dispositif médical formé, préparé à partir d'une composition polymérique en fusion renfermant un ester polymérique, un catalyseur de transestérification et un tri- ou tétra-alcoxysilane. Ce dispositif est formé selon un procédé consistant à former et à solidifier ladite composition, puis, après solidification, à soumettre la composition à des conditions de réaction permettant d'obtenir, d'une part, une hydrolyse d'au moins certains groupes alcoxysilyle présents dans la composition, pour former des groupes silanol, et, d'autre part, une condensation desdits groupes silanol, pour former un réseau de céramique. L'ester polymérique peut être un homopolymère ou un copolymère d'ester vinylique, ou un polymère comprenant des groupes ester dans son squelette.

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