Medical device for vessel compatibility during high pressure...

A - Human Necessities – 61 – M

Patent

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Details

A61M 25/10 (2006.01) A61M 29/00 (2006.01) A61M 29/02 (2006.01)

Patent

CA 2660070

The application provides devices that can be used to deliver a therapeutic agent to a treatment site within the vessel of a patient at increased pressure, while limiting the contact with and pressure placed on the vessel walls. Devices according to the application include an expandable structure (100) arranged around and on a tube (130) having a lumen (140). The expandable structure may include a sealing ring (111) that makes contact with the interior surface of a vessel to prevent or decrease fluid flow during delivery of a therapeutic agent. This allows delivery of a therapeutic agent with decreased risk of injury to the treatment site. The application also provides for large lumen diameters, preventing shearing stress on therapeutic agents such as cell slurries.

L'invention concerne des dispositifs pouvant être utilisés pour administrer un agent thérapeutique à un site de traitement à l'intérieur du vaisseau d'un patient à une pression accrue, tout en limitant le contact avec le vaisseau et la pression placée sur les parois de vaisseau. Les dispositifs selon l'invention comprennent une structure expansible disposée autour et sur un tissu ayant un lumen. La structure expansible peut comprendre un anneau de scellement qui entre en contact avec la surface intérieure d'un vaisseau pour prévenir ou diminuer l'écoulement de fluide pendant l'administration d'un agent thérapeutique. Ceci permet l'administration d'un agent thérapeutique avec un risque diminué de lésion au site de traitement. L'invention permet également d'assurer de larges diamètres de lumen, empêchant une contrainte de cisaillement sur les agents thérapeutiques tels que des bouillies de cellules.

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