Medical device having a biocompatible coating and oxidation...

Details Medical device having a biocompatible coating and oxidation... Medical device having a biocompatible coating and oxidation...

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61C 8/00 (2006.01) A61F 2/06 (2006.01) A61F 2/12 (2006.01) A61L 27/28 (2006.01) A61L 27/34 (2006.01) A61L 31/08 (2006.01) A61L 31/10 (2006.01)

Patent

CA 2245683

This invention is a medical device for implantation in the tissue of a human body having a biocompatible coating thereon comprising a foreign body (11) formed of a material which is substantially biocompatible with the tissue of the human body. The foreign body (11) has a surface (16) adapted to come in contact with the tissue of the human body and is capable of being oxidized. The coating includes an organic linker (26) which is carried on the surface (16) and forms an oxidative coupling with the surface (16). A bioactive agent (32) is bonded to the organic linker (26) by a chemical reaction or photochemical function.

La dispositif médical de la présente invention, destiné à l'implantation dans le tissu d'un corps humain, est pourvu d'un revêtement biocompatible constitué d'un corps étranger (11) fait d'un matériau sensiblement biocompatibles avec le tissu du corps humain. Ce corps étranger (11), dont la surface (16) est conçue pour entrer en contact avec le tissu du corps humain, est capable de s'oxyder. La surface (16) du revêtement inclut un liant organique (26) formant un couplage oxydatif avec la surface (16). Une réaction chimique ou une fonction photochimique assura la liaison d'un agent bioactif (32) au liant organique.

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