Medical device with biomolecule-coated surface graft matrix

Details Medical device with biomolecule-coated surface graft matrix Medical device with biomolecule-coated surface graft matrix

A - Human Necessities

61

L

A61L 27/00 (2006.01) A61L 27/22 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 29/00 (2006.01) A61L 29/04 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/00 (2006.01) A61L 31/04 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) A61L 33/00 (2006.01) A61L 33/12 (2006.01)

Patent

CA 2206147

A medical device having a surface graft matrix comprising carboxyl-functional groups located on the device, the surface graft matrix comprising an outer portion; and one or more biomolecules covalently coupled to the surface graft matrix, wherein a majority of the biomolecules are located in the outer portion of the surface graft matrix. The surface graft matrix can also be loaded with a pharmaceutical agent.

Dispositif médical possédant une matrice de greffe superficielle, avec des groupes carboxyles sur le dispositif, la matrice comportant une partie externe; une ou plusieurs biomolécules sont liées par covalence à la matrice, la majeure partie des biomolécules étant situées dans la partie extérieure de la matrice. Celle-ci peut également être chargée d'un agent pharmaceutique.

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