Medical devices containing in-situ generated medical compounds

Details Medical devices containing in-situ generated medical compounds Medical devices containing in-situ generated medical compounds

A - Human Necessities

61

L

A61L 29/00 (2006.01) A61F 2/04 (2006.01) A61F 2/06 (2006.01) A61L 27/00 (2006.01) A61L 27/50 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 29/18 (2006.01) A61L 31/00 (2006.01) A61L 31/16 (2006.01) A61L 31/18 (2006.01) A61M 31/00 (2006.01)

Patent

CA 2261806

A process for impregnating a medical device made from a water absorbable polymer material, e.g., a hydrogel, with a medical compound having low solubility in aqueous solutions, e.g., an antiseptic or radiopaque compound, is disclosed. The device is first infiltrated with an aqueous solution containing a first water soluble, ionizable compound, and subsequently infiltrated with an aqueous solution containing a second water soluble, ionizable compound. The ionizable compounds are selected such that they react after mutual contact to form the medical compound in-situ within the device.

Procédé d'imprégnation d'un dispositif médical à base de polymère absorbant l'eau, par exemple, un hydrogel, au moyen d'un composé médical à faible solubilité en solution aqueuse, par exemple, un composé antiseptique ou opaque aux rayonnements. On infiltre d'abord le dispositif avec une solution aqueuse renfermant un premier composé hydrosoluble ionisable, puis avec une solution aqueuse renfermant un deuxième composé hydrosoluble ionisable. Les composés ionisables choisis sont capables de réagir après contact mutuel pour déboucher sur la formation in situ du composé médical dans le dispositif.

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