Medical devices for use in the surgical treatment of...

A - Human Necessities – 61 – N

Patent

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A61N 1/00 (2006.01) A61K 9/22 (2006.01)

Patent

CA 2733252

Provided herein are new methods for the treatment of hyperproliferative diseases affecting the spinal cord, including the use of biodegradable polymers to treat spinal cord tumor recessing, i.e., to patch open zones left by spinal tumor removal. Biocompatible polymeric materials are tailored to fill areas previously occupied by tumors, e.g., materials in the form of tubular articles configured for insertion into the spinal column after surgical removal of a tumor. These protective articles may also include medicinal agents that stimulate spinal column neural regeneration, such as medicines or donor neuronal cells such as human neural stem cells, thus assisting patients to recover motorsensory function after spinal tumor surgery.

L'invention porte sur de nouveaux procédés de traitement des maladies hyperprolifératives affectant la moelle épinière, comprenant l'utilisation de polymères biodégradables pour traiter une tumeur de moelle osseuse récessive, c'est-à-dire, pour réparer des zones ouvertes laissées par le retrait de la tumeur de moelle osseuse. On personnalise des matériaux polymères biocompatibles pour remplir les zones précédemment occupées par des tumeurs, c'est-à-dire, des matériaux sous la forme d'éléments tubulaires configurés pour une introduction dans la colonne vertébrale après retrait chirurgical d'une tumeur. Ces éléments protecteurs peuvent également comprendre des agents médicinaux qui stimulent une régénérescence neurale de la colonne vertébrale, telle que des médicaments ou des cellules neuronales donneuses telles que des cellules souches neuronales humaines, aidant ainsi les patients à récupérer une fonction motosensorielle après une chirurgie de tumeur de moelle osseuse.

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