Medical devices having antimicrobial coatings thereon

Details Medical devices having antimicrobial coatings thereon Medical devices having antimicrobial coatings thereon

A - Human Necessities

61

L

A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) G02B 1/04 (2006.01)

Patent

CA 2504259

The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial LbL coating containing one or more antimicrobial peptides. The antimicrobial coating of the invention can impart to the medical an increased surface hydrophilicity and a relatively high antimicrobial activity coupled with low cytotoxicity. The antimicrobial coating of the invention has a minimal adverse effects on the desirable bulk properties of a contact lens, such as oxygen permeability, ion permeability, and optical properties. An antimicrobial coating of the present invention may find particular use in extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having an antimicrobial LbL coating thereon.

L'invention concerne un dispositif médical, de préférence une lentille de contact, qui comprend un revêtement antimicrobien, enduit couche par couche (LbL), contenant un ou plusieurs peptides antimicrobiens. Le revêtement antimicrobien de l'invention, peut conférer un caractère hydrophile de surface amélioré au dispositif médical ainsi qu'une activité antimicrobienne relativement élevée, associée à une faible cytotoxicité. Le revêtement antimicrobien de l'invention présente des effets indésirables minimes en ce qui concerne les propriétés générales d'une lentille de contact, telles que la perméabilité à l'oxygène, la perméabilité aux ions et des propriétés optiques. Ledit revêtement antimicrobien peut être utilisé en particulier dans des lentilles de contact à port prolongé. De plus, l'invention concerne un procédé de fabrication d'un dispositif médical, de préférence une lentille de contact, présentant un revêtement antimicrobien, enduit couche par couche (LbL).

Affiliated with

Also associated with

Rating

Medical devices having antimicrobial coatings thereon does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Medical devices having antimicrobial coatings thereon, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medical devices having antimicrobial coatings thereon will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1762837