Medical devices having nanostructured coating for...

Details Medical devices having nanostructured coating for... Medical devices having nanostructured coating for...

A - Human Necessities

61

L

A61L 31/14 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2662473

A medical device having a biodegradable coating comprising an inorganic material complexed to macromolecules. Biodegradation of the biodegradable coating releases nanoparticles of the inorganic material with macromolecules complexed to the released nanoparticles. The inorganic material may be applied directly onto the medical device as a nanostructured coating or be dispersed within or under a layer of biodegradable polymer. The medical device body may comprise a biodegradable metallic material. Also provided is a method of delivering macromolecules to body tissue using the medical device of the present invention.

L'invention concerne un dispositif médical ayant un revêtement biodégradable comprenant une matière inorganique complexée à des macromolécules. La biodégradation du revêtement biodégradable libère des nanoparticules de la matière inorganique avec des macromolécules complexées aux nanoparticules libérées. La matière inorganique peut être appliquée directement sur le dispositif médical en tant que revêtement nanostructuré ou être dispersé à l'intérieur de ou sous une couche de polymère biodégradable. Le corps du dispositif médical peut comprendre un matériau métallique biodégradable. L'invention concerne également un procédé d'administration de macromolécules à un tissu corporel à l'aide du dispositif médical de la présente invention.

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