Medical devices having porous layers and methods for making...

Details Medical devices having porous layers and methods for making... Medical devices having porous layers and methods for making...

A - Human Necessities

61

F

A61F 2/06 (2006.01)

Patent

CA 2503625

Methods for fabricating a medical device (20) having at least one porous layer include providing a medical device (20) having at least one alloy and removing at least one component of the alloy to form the porous layer. Although methods may be used to make stent (10) devices with porous layers (12, 14), any other suitable medical device may be made having one or more porous layers. An alloy may include any suitable combination of metals and sometimes a combination of metal and non-metal. In some embodiments, one or more of the most electrochemically active component(s) of an alloy are removed by the dissolving (or "dealloying") process, to leave a porous matrix behind. The porous matrix layer may then be infused with one or more therapeutic agents for enhancing treatment of a patient.

L'invention concerne des procédés de fabrication d'un dispositif médical comportant au moins une couche poreuse, consistant à utiliser un dispositif médical comprenant au moins un alliage et à retirer au moins un composant de l'alliage pour former la couche poreuse. Bien que ces procédés servent à fabriquer des stents avec des couches poreuses, ils permettent également de fabriquer d'autres dispositifs médicaux comportant une ou plusieurs couches poreuses. Un alliage peut comprendre n'importe quelle combinaison de métaux et éventuellement une combinaison d'un métal et d'un non-métal. Dans certains modes de réalisation, un ou plusieurs des composants les plus actifs sur le plan électrochimique d'un alliage sont retirés par procédé de dissolution (ou <= désalliage >=), pour obtenir une matrice poreuse. Cette matrice poreuse peut ensuite être injectée par perfusion avec un ou plusieurs agents thérapeutiques pour rendre plus efficace le traitement d'un patient.

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