Medical use of ras antagonists for the treatment of...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A61K 31/00 (2006.01)

Patent

CA 2515519

The invention relates to the field of vascular anomalies and methods for diagnosing and treating them. The invention provides for the causative gene (RASA1) and mutations therein which are useful for diagnosing inherited capillary malformations. The invention further provides RASA1 antagonists for use in treatment of capillary malformations.

L'invention se rapporte au domaine des anomalies vasculaires et aux méthodes de diagnostic et de traitement de celles-ci. L'invention concerne le gène causal (RASA1) et les mutations que l'on utilise pour diagnostiquer les malformations capillaires héréditaires. L'invention concerne en outre les antagonistes RASA 1 servant au traitement de malformations capillaires.

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