A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01)
Patent
CA 2611418
A medicament carrier composition includes a medicament and a polymer component including a polyvinylpyrrolidone having a weight average molecular weight of at least 700,000 g/mol. The medicament carrier composition has a viscosity of from 500 to 5,000 cps at 250C, is substantially free of cellulose, and includes an auxiliary polymer. The medicament carrier composition is used to form a film that is also substantially free of cellulose. The film has a consistent thickness and size, and an increased flexibility and increased moisture resistance due to the polyvinylpyrrolidone. The medicament carrier composition is also used in a method of forming the film. The method includes the steps of providing the medicament and the polymer component. The method also includes the step of combining the polymer component and the medicament to form the medicament carrier composition. The method further includes the step of drying the medicament carrier composition to form the film.
La présente invention concerne une composition de porteur de médicament qui comprend un médicament et un composant polymère comprenant un polyvinylpyrrolidone possédant un poids moléculaire moyen d'au moins 700,000 g/mole. Cette composition de porteur de médicament possède une viscosité comprise entre 500 et 5,000 cps à 250C, est sensiblement exempte de cellulose et comprend un polymère auxiliaire. Cette composition de porteur de médicament est utilisée pour former un film qui est également sensiblement exempt de cellulose. Ce film possède une épaisseur et une taille consistante, et une souplesse améliorée ainsi qu'une résistance à l'humidité accrue grâce au polyvinylpyrrolidone. Cette composition de porteur de médicament est également utilisée dans un procédé de formation de film. Ce procédé consiste aussi à combiner le composant polymère et le médicament de façon à former cette composition de porteur de médicament. Ce procédé consiste aussi à déshydrater cette composition de porteur de médicament de façon à former le film.
Ali Shaukat
Quadir Anisul
Basf Corporation
Gowling Lafleur Henderson Llp
LandOfFree
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